A retrospective correlative study on serum testosterone level and type-2 diabetes

Abstract

Introduction: Testosterone is a hormone that plays a key role in male health and development. However, it is also linked to diabetes, a metabolic disorder affecting many individuals all over the world. Those with diabetes have an increased chance of developing low testosterone levels, while those with low testosterone levels may be at a higher risk of developing diabetes. Aim and Objective: Present study was conducted to find the link between testosterone and diabetes in order to determine whether low testosterone levels can lead to diabetes. Materials and Methods: The study was conducted in men, who were diagnosed as type 2 diabetes mellitus patients and confirmed by the estimation of FBS, PPBS, and HbA1C. Healthy age and BMI matched individuals, were selected as controls. The laboratory investigations included evaluation of serum testosterone levels and creatinine was carried out by standard method. Result and Discussion: The results showed that low testosterone levels in men could be linked to an increased risk of developing type 2 diabetes. The exact mechanism behind this is still unknown, but it appears to be a result of the testosterone's ability to affect glucose metabolism. Low testosterone levels can lead to a decrease in insulin sensitivity, which can eventually lead to diabetes. Conclusion: Overall, it appears that there is a link between testosterone and diabetes, with low testosterone levels in men potentially leading to an increased risk of developing diabetes. It is important to maintain healthy testosterone levels in order to reduce the risk of diabetes.