Glioblastoma and COVID-19 in an elderly patient about a case: Review of the literature

Abstract

The coronavirus 2 epidemic responsible for severe acute respiratory syndrome (SARS-CoV-2) has an impact on the management of glioblastomas and changes perioperative practice worldwide in case of comorbidity. We report the first case in the literature of an association of Glioblastoma and COVID-19 in an elderly subject. The assumptions made below will likely confirm further studies in the future. This is a 65-year-old patient whom we followed for Glioblastoma. He was hospitalized in the emergency room of the Fann University Hospital in Dakar due to disorders of consciousness. It was during hospitalization at the émergence room that he probably contracted COVID-19 then treated and declared cured. After healing, a slight improvement in disturbances of consciousness was observed. The patient then underwent a subtotal excision of his brain tumor with a histopathological exam. It was a glioblastoma. We can say that COVID-19 infection delays the management of patients with Glioblastoma. This single case report only suggests an association between COVID-19 infection and Glioblastoma. We encourage other authors to share their experiences to confirm our hypotheses and formulate therapeutic guidelines.