Assessing the impact of gut-origin probiotic supplementation on haemato-biochemical and antioxidant profiles in neonatal murrah buffalo calves

Abstract

This study explores the less investigated aspects of probiotics, focusing on their influence on haemato-biochemical and antioxidant profiles. These profiles encompass blood markers and biochemical parameters, offering insights into overall physiological health. The study specifically evaluates the impact of the gut-derived probiotic Pediococcus pentosaceus on haemato-biochemical and antioxidant profiles in neonatal Murrah buffalo calves over a four-month trial period. The experiment involved two groups, control and treatment, with probiotic supplementation to the latter. Haematological and serum biochemical parameters were assessed at 0 and 4 months of feeding trial. The probiotic, P. pentosaceus RM119, was administered at 108 CFU/calf/day. Various haematological parameters, serum biochemical and erythrocytic antioxidant profile were investigated. Statistical analysis revealed no significant impact on haematological parameters. Serum biochemical profiles remained within normal ranges, indicating the overall well-being of experimental animals. Erythrocytic antioxidant glutathione showed an increase, suggesting a potential positive influence on antioxidant defenses. The study concludes that P. pentosaceus RM119 supplementation is safe and may offer health benefits in buffalo calves, warranting further exploration in animal health and welfare.