A study on co-infection of bovine parainfluenza 3 virus (BPI3V) and bovine respiratory syncytial virus (BRSV) in cattle

Abstract

Background: Pneumonia in livestock is attributed for major economic loss to the poor and marginal farmers in terms of the expenditure on medicine, veterinary, reduced production by death of the animal. Bovine parainfluenza 3 virus (BPI3V) and bovine respiratory syncytial virus (BRSV) are the two main viral respiratory infections that cause substantial morbidity and death. Aim: The aim of present study was to investigate co-infection of Bovine Parainfluenza 3 Virus (BPI3V) and Bovine Respiratory Syncytial Virus (BRSV). Methods: Tissue samples from 32 cattle presented for post-mortem examination were collected in 10% NBF and processed for histopathological evaluation. The pathological lesions were observed for the severity and extent of lesions including inflammatory reaction. PCR assays were performed to detect the nucleic acid of BPI3V and BRSV in the tissue samples. Results: Out of 32 tissue samples, 6.25% (2/32) were found to be affected with co-infection of Bovine Parainfluenza 3 Virus (BPI3V) and Bovine Respiratory Syncytial Virus (BRSV). Conclusion: This finding concludes that co-infection of Bovine Parainfluenza 3 Virus (BPI3V) and Bovine Respiratory Syncytial Virus (BRSV) prevails and is one of the causes of pneumonia and production losses to cattle industry.