Comparative analysis of TLR6 of Camelus dromedarius across distant species

Abstract

Toll-like receptors (TLRs) constitute a multi-gene family of Pattern recognition receptors in vertebrate’s genome. These are having a crucial role in defence mechanism against invading pathogens. Our present investigation was carried out to comparative analysis of the TLR6 of dromedary camel with twelve other species. At the amino acid level, the TLR6 dromedary camel showed highest similarity with Camelus bactrianus (99.88%) and Camelus ferus (99.76%) followed by Bos taurus (86.13%). While, minimum similarity was observed with Oryctolagus cuniculus (76.88%). On the basis of amino-acid sequence, phylogenetic tree revealed close relationship with camelid species followed by cattle, pig whereas, distantly placed were human, gorilla, and rabbit.