Transcranial doppler echo in children with sickle cell SS in Niger: Velocimetric study

Abstract

Aim: The aim of our work is to study the velocities by trans cranial Doppler in children with homozygous sickle cell SS, more specifically to measure cerebral circulatory velocities by trans cranial oppler in children with sickle cell SS and determine the relationships between the results of trans cranial Doppler with the age and type of sickle cell disease.Materials and Methods: We conducted a retrospective prospective study (October 2018 to December 2020) and over a period of 27 months.Results: We recruited a total of 126 patients aged between 1 year and 15 years. The sex ratio is 1.2. The average systolic velocities at the level of the right and left middle cerebral artery are abnormally high respectively with a rate of 61.90% and 58.73%. In total we had 68.25% (n=86) of patients with high risk, 9.52% (n=12) with intermediate risk.Conclusion: Sickle cell disease is one of the most common genetic pathologies in our regions, especially the homozygous form. The latter is the one that presents more complications and among which we have Stroke. Stroke detection is done using transcranial Doppler, hence the purpose of our study.