Aggregatibacter actinomycetemcomitans: A scoping review

Abstract

he etiology and pathophysiology of many neurodegenerative diseases and neuropsychiatric disorders, as well as in systemic diseases and cardiovascular diseases, as they generate in the immune system a dysregulation.Objective: To analyze the literature on A. actinomycetemcomitans, with a focus on the dental field, analyzing its epidemiology, diagnostic methods, treatments and oral manifestations.Methodology: Information from articles published in PubMed, Scopus and Google Scholar was analyzed with emphasis on the last 5 years. It was performed with the words ""Aggregatibacter actinomycetemcomitans", "periodontal disease", "epidemiology", "oral manifestations", “diagnosis”, "treatment".Results: A. actinomycetemcomitans is found approximately 90% in cases of aggressive periodontitis, and 21% in patients with chronic periodontitis. The common diagnostic method for periodontopathogenic bacteria is by quantitative PCR. Treatment is based on a combination of mechanical and antibiotic therapy for best results. Clinical evaluation shows clinical attachment loss, severe bone destruction at an early age with rapid progression, causing mobility and tooth loss.Conclusions: The presence of this pathogen generates an environment that requires mechanical, chemical and antimicrobial procedures for its long-term control, so a timely diagnosis leads to the early establishment of therapies for the management of the infection.