Irritable bowel syndrome frequency and related factors in hemodialysis patients

Abstract

Background: The incidence of gastrointestinal system (GIS) issues in patients with chronic kidney disease (CKD) is quite high. IBS, one of the GIS disorders, is more prevalent among patients undergoing dialysis. Patients with IBS are more susceptible to psychiatric disorders such as depression and anxiety (CKD). The purpose of the work: is determining the prevalence of IBS and its associated factors among CKD patients undergoing hemodialysis. Method and materials: A cross-sectional research was conducted on a group of 200 patients who were receiving hemodialysis. The patients were categorized into two distinct groups: Group A: 100 patients of CKD on hemodialysis and Group B: 100 patients of CKD on non-hemodialysis treatment. All Patients diagnosed to have IBS in hemodialysis according to ROME IV criteria. The presence of depression and anxiety was assessed using the Hamilton Depression Rating Scale (HAM-D) and the Hamilton Anxiety Rating Scale (HAM-A). Results: In our study IBS in hemodialysis group was significantly (59%) in comparison to non-hemodialysis CKD group was (44%). In this current study we had found depressive symptoms in a significant percentage of patients more than (64%) among those in dialysis and (47%) among those in non-hemodialysis CKD group. In our study, we had found anxiety symptoms in a significant percentage of patients more than (62%) among those in dialysis and (41%) among those in non-hemodialysis CKD group. Patients with IBS had substantially higher ratings for anxiety and sadness compared to those without IBS (p<0.029 and p<0.001, respectively). Conclusion: Patients undergoing hemodialysis were more likely to have IBS, according to our research. A greater prevalence of depression and anxiety was observed as well in the hemodialysis group when contrasted with the non-hemodialysis CKD group.