Microwave assisted organic synthesis of nitrogen, oxygen and sulphur containing heterocycles

Abstract

Microwave assisted organic synthesis is one among the handy methods included in Green Chemistry. The main objective of this work was to synthesize useful nitrogen, oxygen and sulphur containing heterocyclic compounds. Generally, such heterocyclic compounds are of prime interest when medicinal chemistry is concerned for their pronounced response towards various pharmacological tests. Apart from this, basically their synthetic route is of much importance. Use of solvent free reaction conditions enable eco-friendly synthesis of heterocycles. Likewise, coumarin, chalcone and amino thiadiazole derivatives were prepared using various starting materials to promote green synthesis. Knoevenagel, Schiff base formations etc. helped mechanistically to understand the way of product formations. Selected compounds were subjected for various characterization techniques like FT-IR, 1H NMR, 13C NMR and LCMS for strong conclusion.