Clinical validation of unani pharmacopoeial formulation Majoon-e-Piyaz in Surat-e-Inzal (Premature ejaculation)

Abstract

Each participant was well informed about the trial and written consent was obtained before initiation of the study. Demographic data and information on the present disease condition, concomitant disease and therapy was recorded. Thorough general physical and systemic clinical examination was carried out. Signs and Symptoms pertaining to premature ejaculation were recorded in CRF. The vital parameters like blood pressure, heart rate, temperature and respiratory rate were also recorded. Blood sample were collected for the evaluation of laboratory parameters like Haemogram, complete blood picture, kidney function test, liver function test and routine and microscopic examination of urine were done. All clinical and laboratory follow up were done at every 4 weeks.The study was carried out in a total number of 105 patients of premature ejaculation satisfying the criteria, 80 patients completed the trial. All the patients received treatment with Majoon-e-Piyaz, out of 80 subjects 06 patients got complete remission, 47 patients got partially remission, 27 patients showed poor remission and 25 patients dropped out. No hepatotoxic and nephrotoxic side effects noticed during the course of study. The clinical and laboratory findings after treatment have shown that Majoon-e-Piyaz possessed efficacy in the treatment of premature ejaculation.