Anthelmintic activity of methanolic extract of Euphorbia milii

Abstract

The purpose of this study was to examine the anthelmintic activity of Euphorbia milii (E. milii) leaves, which were selected as a different source of potent treatments for nematodiasis. The anthelmintic activity of E. milii was tested in adult Pheretima posthuma Indian earthworms. The reference standard was albendazole (10 mg/ml), while the control treatment was normal saline (10 ml). The extracts were tested at various methanolic concentrations (20 mg/mL, 40 mg/mL, 80 mg/mL, and 100 mg/mL). To report the earthworms' paralysis and death time, the data were stated in terms of time in minutes. The study's observations have led to anthelmintic action, supporting traditional use of both plants when compared to the standard.