Antibiogram of bacteriuria among pregnant women in urban informal settlements in Port Harcourt municipality

Abstract

Bacteriuria during pregnancy is a common concern, as it is associated with adverse maternal and fetal outcomes. This study aimed to assess the antibiogram of bacteriuria among pregnant women residing in urban informal settlements within Port Harcourt Municipality, Nigeria. A cross-sectional study was conducted, involving pregnant women attending antenatal health care centers in informal settlements. Midstream urine samples were collected and cultured to identify bacterial pathogens. Antimicrobial susceptibility testing was performed using standard laboratory methods, and antibiograms were constructed to determine the resistance patterns of isolated bacteria. The results of antimicrobial susceptibility testing indicated high levels of resistance of the isolated bacteria such as Escherichia coli, Staphylococcus sp and Enterococcus to commonly prescribed antibiotics, including Ceftazidime, Cefuroxime, and Augmentin, among others. Notably, a considerable proportion of isolates remained susceptible to nitrofurantoin, gentamycin and ciprofloxacin. This study underscores the urgent need for revising empirical antibiotic treatment guidelines for bacteriuria in pregnant women in urban informal settlements. The high levels of antibiotic resistance observed highlight the importance of tailored treatment strategies and antimicrobial stewardship programs to ensure the well-being of both mothers and infants.