Evaluation of TSH level in the first trimester of pregnancy in women with no history of thyroid Disorder referred to Imam Khomeini and Razi Hospital of Ahvaz

Abstract

Pregnancy causes physiological changes in maternal thyroid function tests and changes are occasionally confused with thyroid abnormalities, therefore the aim of this study was to determine the TSH levels in the first trimester of pregnancy in women without a history of thyroid disease. And to determine the importance of screening of thyroid diseases in early pregnancy. Methods: This descriptive analytic study consisted of 1200 pregnant mothers in their first trimester referring to Jondishapur university hospitals for prenatal care in the span of one year. Cases with incomplete data as well as pregnant mothers with a history of thyroid disorders were excluded. In addition to routine prenatal lab test TSH level was measured by enzyme-linked immunosorbent assay (ELISA) method. It should be noted that the documented information is confidential and will not be used in any other study. All TSH measured data was analyzed by SPSS software version 26 and All P values 0.05). However, there was a significant correlation between BMI, family history of thyroid diseases and hypertension in pregnant women without past medical history of thyroid diseases and TSH level in the first trimester of pregnancy (p