The relation between vascular access and development of contrast induced nephropathy in patients undergoing percutaneous coronary intervention

Abstract

Background: Contrast induced nephropathy (CIN) could be a serious outcome complicating percutaneous coronary intervention (PCI) patients affecting both morbidity and mortality. The aim of this work was to study the relation between vascular access and development of contrast induced nephropathy in patients undergoing PCI. Methods: This prospective study was carried out on 300 patients aged above 18 years old undergoing PCI. Patients were divided in to two equal groups: Group I: underwent trans-femoral PCI. Group II: underwent trans-radial PCI. Results: There was no significant difference in minimizing the risk of CIN between the two comparable approaches. In multivariate logistic regression analysis, the volume of contrast used was a significant parameter increasing the incidence of CIN [P value 0.025, OR (95% C.I) 1.020 (1.002-1.037)]. Also, patient’s left ventricle ejection fraction after PCI was found to be significant parameter affecting the incidence of CIN [P value 0.028, OR (95% C.I) 0.919(0.852-0.991)]. Conclusions: Radial access for PCI isn't inferior to femoral access as regards risk of CIN in patients undergoing PCI.