In vitro α- amylase inhibitory and anti-inflammatory activity of Butea monosperma silver nanoparticles

Abstract

In this research, silver nanoparticles were synthesized from Butea monosperma for in-vitro α-amylase inhibitory and anti-inflammatory activity. Because of the improved microbiological resistance to antibiotics and medications, silver nanoparticles are rated the most positive due to their large volume surface region. As a result, green synthesis of silver nanoparticles using biomolecules derived from various plant sources in the form of extracts can be used for disease screening and physical and biological characterization of plant-derived silver nanoparticles. The green synthesis of silver nanoparticles (AgNPs) from Butea monosperma leaf extract was the subject of the experiment. UV-visible spectroscopy, used to analyse biosynthesized Butea monosperma-AgNPs. The intensity of the peak broad range 200-800 nm in UV-Visual spectra, an in vitro anti-diabetic activity was evaluated by α-amylase inhibition method while anti-inflammatory by albumin denaturation assay. At the concentration of 1000 µl of compound, the sample A (water) and D (acetone) showed good α-Amylase Inhibitory activity and showed more percent inhibition of protein denaturation as compared with standard.