Autologous platelet rich plasma therapy in Orthopedics: An update

Abstract

Recent advances in molecular and nanobiology have led to the identification of specific cytokines that mediate cellular activities which becomes a powerful tool in management of orthopaedic disorders. Platelet rich plasma is a potential “Orthobiologic” agent for treating inflammatory and degenerative musculoskeletal disorders. Platelet rich plasma therapy aimed in rejuvenating the degenerating tissues by neoangiogensis and neoinnervation thus by increasing the texture and biology of the diseased tissues. This article outlines the guidelines for the usage, precautions, pre and post injection events of autologous platelet rich plasma therapy in musculoskeletal disorders.