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Synthesis and antiviral activity of 2-3,5 dinitropheny1-5-substituted phenyl 1,3,4-oxadiazoles
International Journal of Advanced Academic Studies · 2020 · Vol. 2(3) · pp. 262–263
Abstract
3, 5 dinitro benzoic acid hydrazide was prepared by the hydrazinolysis of the corresponding ethyl ester. Condensation of this hydrazide with different aromatic acids in presence of POCl3 gave 2-3, 5 dinitropheny1-5-substituted pheny1 1, 3, 4-oxadiazoles. All the final compounds were tested against Ranikhet Disease Virus (RDV). However no compound showed antiviral activity against RDV.
Insect and Pesticide ResearchStructural and Chemical Analysis of Organic and Inorganic CompoundsSynthesis and biological activityHydrazideChemistryBenzoic acidCondensationOrganic chemistryCombinatorial chemistryMedicinal chemistry
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