Prediction of coronary artery disease severity from platelet to lymphocyte ratio

Abstract

Background: Previous reviews confirmed the fundamental relation between numerous hematologic variables particularly neutrophil/ lymphocyte ratio and coronary artery disease (CAD). Predictive and more notable prognostic significance of the neutrophil/lymphocyte ratio has been clearly shown in several cardiac and vascular diseases. The goals of this research include determining the platelet to lymphocyte ratio's (PLR) values as a measure of the extent of coronary atherosclerosis, determining the correlation between PLR and atherosclerosis severity in CAD, and determining the PLR cut-off value that indicates severe CAD. Methods: This case-controlled work was performed on 180 individuals planned for elective diagnostic coronary angiography. The participants were split into three equal groups regarding coronary angiography and Gensini score. Group I: 60 participants with normal coronary angiography and zero Gensini score. Group II: 60 participants with mild atherosclerotic CAD and Gensini scores of