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Gestational pemphigoid

Abstract

Pemphigoid gestationis is a rare, autoimmune blistering dermatosis. It is unique in that it is diagnosed primarily in association with pregnancy. Autoantibodies against placental BP180 (also known as BPAG2 or collagen XVII) cause damage to the skin basement membrane, resulting in severe itching and blistering rash over the body and the extremities.

Autoimmune Bullous Skin DiseasesCoagulation, Bradykinin, Polyphosphates, and AngioedemaUrticaria and Related ConditionsItchingDermatologyMedicineBullous pemphigoidPemphigoidRashBasement membranePregnancyPathologyImmunology
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Gestational pemphigoid · Scinovex