Congenital rubella syndrome-A meta-analysis

Abstract

Congenital rubella syndrome (CRS) is an illness in infants that result from maternal infection with rubella virus during pregnancy. When rubella infection occurs during early pregnancy serious consequences such as miscarriage, stillbirth, birth defects can occur in infant. Burden of congenital rubella syndrome on the society is increasing and it is still not fully recognized. Surveillance of the cases and routine vaccination can help the people and society to get rid of this disease. In this review study focus is on disease pathology, epidemiology, pathogenesis, clinical manifestations and different strategies to prevent CRS.