Bıochemıcal study to evaluate the role of heavy metals and oxıdatıve stress ın the ıncıdence of kıdney dısease ın ıraqı patıents

Abstract

The study was conducted on kidney patients (60 male and female, and healthy subjects control n=60, Serum was used to assay antioxidant enzymes activities and to measure MDA to prove such lipid peroxidation occurring as MDA considered an indirect measurement for lipid peroxidation, GSH in control group (11.65±0.01) while the increase in patient male and woman (18.55±0.01, 30±0.01), which MDA in control group (0.227±0. 1) that increase in patient male and woman (0.384±0.02, 0.138±0.01) and GST in control group (3.3±0.01) while the increase in both groups (3.8±0.01, 3.6±0.01). The control group's TAC (4.00±0.32), were calculated. Additionally, the TAC values for renal patients were (2.38±0.55), while in women (2.16±0.34). The mean TAC in patients is significantly decreasing from the control group (p