Role and applicability of lt;emgt;in silico lt;/emgt;molecular interactional studies and analysis in relation to Covid-19 pandemic

Abstract

From December 2019 up till today, COVID-19 has caused a big Havoc across the globe, not to mention the economic crisis it has caused in the nations and has brought everything to a temporary hold. Till date no viable treatment option is available but computational approaches like molecular interactional and docking studies are giving all the researchers a hope. Since the beginning of the pandemic there has been a huge number of researches done on molecular docking and drug repurposing which have upgraded the potential of drugs like lopinavir and remdesivir. These techniques have also targeted protein receptors like ACE2 receptor thus targeting entry of virus particle to the host cells. In this article we have tried to highlight such major points about molecular interactional studies along with its role and applicability in finding a viable and potential treatment option.