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Melatonin and Periodontal Disease: A Review

International Journal of Applied Dental Sciences · 2023 · Vol. 9(2) · pp. 131–137

Abstract

Melatonin is an indoleamine derivative synthesised mainly in the pineal gland. Its association with periodontal disease and periodontal treatment with exogenous supplementation of Melatonin via oral route, topical application and as local drug delivery has been documented as evidences in the literature. This review article focuses on the melatonin functions in periodontium which includes its anti-inflammatory, antioxidant, antiresorptive and immunomodulatory properties.

Circadian rhythm and melatoninSleep and related disordersMelatoninPeriodontiumPineal glandPeriodontal diseaseMedicineDiseaseAntioxidantDentistryPharmacologyInternal medicine
Citations
2
FWCI
0.30
field-weighted impact
References
42
Percentile
52%
vs. same field & year
Citations per year
References
Oxidants, antioxidants, and the degenerative diseases of aging.
Proceedings of the National Academy of Sciences · 1993 · 5,964 citations
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Melatonin and Periodontal Disease: A Review · Scinovex