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Apelin and lipid profile in hypertensive patients a correlation data

Abstract

High blood pressure is directly related to the rise in non-HDL-c harmful fats in the body, as it narrows the arteries and thus increases blood pressure. However, blood pressure decreases significantly with high UHDL-c, so it is considered good fat. Volunteers have divided into two groups the control group included healthy people and the patients’ group involved hypertension. Lipid profile and Apelin were measured for both groups, and apelin was measured using an ELISA kit. As a result, apelin was decreased significantly in hypertension patients’. Also, lipid parameters like TG, LDL-c, and non-HDL-c were elevated. Apelin level in the control group was higher than in the patients’ group, which was a good indicator of normal blood pressure. A low level of apelin in the patients’ group was a bad sign for hypertension, a decrease in apelin concentration in connection with an increase in non-HDL-c levels. So, this maybe increases the risk of hypertension and dyslipidaemia.

Apelin-related biomedical researchParaoxonase enzyme and polymorphismsApelinBlood pressureInternal medicineMedicineEndocrinologyLipid profileBlood lipidsPositive correlationCardiologyCholesterol
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