Formulation and evalution of mouth dissolving tablet of solid dispersion by sublimation technique

Abstract

Mouth dissolving tablets have recently taken an important market position by resolving issues with previous administration and leading to enhancing the patient's life, which have difficulty swallowing tablets. These tablets dissolve/disintegrate into the mouth for easy administration of pharmaceutical ingredients after introduction into the mouth without additional water. Some patients may find it inconvenient to have glass of water. A paediatric patient with allergies may use a dosage is better convenient than antihistamines. These tablets are also more convenient to some patients, who try to hide their daily dose under the tongue, especially schizophrenic patients. When preparing oral drug delivery system, simplicity of administration and improved patient compliances are must involve. The article aims to address ideal properties, advantages, limitations, selection of superdisintegrants and patented techniques of mouth dissolving tablet preparation.