Review on antispasmodic activity of crocus sativus and abies

Abstract

Antispasmodic activity is used to relieve spasm in smooth muscle. Crocus sativus commonly known as saffron belong to iridaceae family, rich in carotenoid used in traditional medicine such as cough, stomach disorders, amenorrhea and asthma. The relaxant effect of crocus sativus on smooth muscle are due to its constituents such as safranal, crocin, crocetin and kaempferol. The therapeutic effects of this plant are also suggested in blood vessels and various smooth muscles. It is used in siddha formulation such as kungamapoo tablet Abies webbiana belong to pinaceae family rich in flavonoids and tannin used for anti-spasmodic, bronchodilator. They show ca++ channel blocking effect. It is main ingredient in siddha formulation such as thalisathichooranam, elathychooranam and thalisathivadagam. In this study, we have investigated antispasmodic activity of Abies webbiana and crocus sativus.