review

Effect of statin therapy on cognition level: A systematic review

International Journal of Pharmaceutical and Clinical Research · 2022 · Vol. 4(2) · pp. 20–25

S Anandkumar✉B Ajith KumarChristina PonnachenSarfaraas Ahamath SD Syed Ali Fathima

Abstract

Statins are a widely prescribed class of drugs to lower cholesterol. On 28 February 2012, the United States Food and Drug Administration (FDA) issued a new warning for the labelling of statin drugs regarding potential adverse effects on cognition. This article aims analyse to review the effect of statin therapy on cognition level. We performed a systematic, computer-aided search of MEDLINE, EMBASE, and the Cochrane Central Register from January 2008 to October 2021. The age wise cognition impairment and pointed out the age group from 61-70 years showed the highest impairment. whereas long-term data suggest a beneficial role in the prevention of dementia.

Lipoproteins and Cardiovascular Health Blood Pressure and Hypertension Studies Computational Drug Discovery MethodsCognitionMedicineAdverse effectMEDLINEDementiaStatinFood and drug administrationCognitive impairmentSystematic reviewPhysical therapy

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