A mini review on recent updates on pharmacological evaluations of molecules based on azetidinones and rhodanines heterocyclic nucleous

Abstract

Azetidinones is a four member heterocyclic ring system with nitrogen as the hetero atom and a carbonyl group incorporated into it. Rhodanines is five-membered heterocyclic molecules containing thiazole nucleus with carbonyl group on fourth carbon such as rhodanine derivatives have broad spectrum of pharmacological activities. Azetidinones and rhodanines were showed wide spectrum activities including antimicrobial, anti-tubercular, anticonvulsant, anticancer, anti-inflammatory and CNS activities etc. The uses of different azetidinone and rhodanine compounds for synthesizing various biologically active compounds. Substituting the azetidinones and rhodanines with appropriate substitution for showing biological activities. Various biological activities of azetidinones and rhodanines are discussed in this article.