An interesting case of Anti-N-Methyl-D-Aspartate receptor encephalitis

Abstract

Anti-N-Methyl-D-Aspartate Receptor Encephalitis (Anti NMDARE) is an immune mediated encephalitis. It is one of the most common cause of acute and sub-acute encephalopathy. Clinical features include behavioral disturbances, psychiatric manifestations, seizures, movement disorders [1]. Here we report a case of 3 year 1 month old girl who presented with difficulty in walking and involuntary movements. There were no other complaints, necessary investigations were sent which pointed towards anti NMDARE, awake EEG showed characteristic delta brush and CSF analysis showed NMDA receptor antibody was positive.