A Clinicopathological study of salivary gland neoplasms in a tertiary care hospital: A three year study

Abstract

Background: The tumors of the salivary glands are uncommon head and neck neoplasms. The aim of this study was to observe the clinical occurrence of salivary gland neoplasms and to study the various histo-morphological features of salivary gland tumours, their frequency, age and sex distribution. Materials and Methods: The cases which have arrived to the Dental OP at Drs Sudha and Nageswara Rao Sidhhartha Institute of Dental Sciences with swellings in the head and neck region were identified and sent to pathology department from June 2013 to May 2016 and cases which were diagnosed as salivary gland neoplasms (96 cases) were taken into consideration and Histopathological examination was done. Results: Out of 96 cases, 51 (53.1 %) were benign and 45(46.9 %) were malignant with M:F ratio of 1.74:1. Age range of patients was from 10 to 80 years. Pleomorphic adenoma was found to be the commonest benign tumor (74.5 %), followed by Warthin’s tumor (19.6%), monomorphic adenoma (3.9 %) and basal cell adenoma (3.9 %). The mucoepidermoid carcinoma was the most common malignant tumor (48.8%) followed by adenoid cystic carcinoma (33.3%), acinic cell carcinoma (13.3%), adenocarcinoma NOS (2.2%) polymorphous adenocarcinoma (2.2%) Conclusion: Males were more affected than females and pleomorphic adenoma was the most frequent lesion followed by warthin’s tumor among benign neoplasms. Mucoepidermoid carcinoma is the most common malignant neoplasm followed by adenoid cystic carcinoma.