Association between the serum CRP level and different subtypes in Non-Small Cell Lung Cancer

Abstract

Background: C-reactive protein (CRP) was discovered in 1930 and is widely used as a sensitive, but nonspecific, marker of systemic inflammation. C-reactive protein (CRP) is the prototype acute-phase protein, which can increase up to 1000-fold after the onset of a stimulus. Aside from its disputed role as a marker of infection and/or inflammation in daily clinical practice, the protein has a wide variety of biological properties and functions. Increased serum CRP (s-CRP) levels have been reported in many pulmonary disorders, including pneumonia, malignancies, and pulmonary thromboembolism.