Effectiveness of dynamic homoeopathic preparation of Nux vomica in reducing the craving for alcohol in dependent subjects

Abstract

Background: Alcohol is one of the main contributors to diseases world-wide which leads to a potentially preventable death. Alcohol use disorders are the most prevalent of all substance use disorders. Alcohol dependence poses physical, psychological, economic and social issues to the individual, families and community. Objectives: To assess the effectiveness of Nux Vomica 1M in reducing the craving for alcohol in dependent subjects.Materials and Methods: Cases presenting with Alcohol dependence are assessed with Penn Alcohol Craving Scale (PACS) and Severity of Alcohol Dependence Questionnaire (SADQ) for craving and dependence respectively. Nux vomica 1M was given orally twice a day for 8 weeks. The data obtained from the pre and post treatment was statistically analyzed. Results: Paired sample t test showed that there is a statistically significant difference between the before and after PACS scores (t=9.55, df=29, p< 0.001) with a mean difference of 7.77±0.81(95%CI: 6.10to 9.43). The before and after scores of SADQ were significantly different (t=8.94, df=29, p