Study of placental maturity by ultrasound in pregnancy with sickle cell disease/trait & correlation with normal pregnancy

Abstract

Aims and Objectives: The aim of the study is to evaluate the effect of sickle cell disease/trait on the maturation of placenta and further correlation with maturation of placenta in normal individuals.Material and Methods: Antenatal ultrasound of 45 pregnant patients from each three different categories (i.e., sickle cell disease; sickle cell trait and normal) was done. Sickle cell disease (SCD) and Sickle cell trait (SCT) patients were diagnosed on the basis of serum electrophoresis test. The degree of placental maturation, thickness and location of the placenta evaluated. The data collected from the subjects then further compared for any difference between the degree of maturity between three study groups. Results: The correlation between placental grading and gestational age in all three categories was not statistically significant (P value > 0.05). Conclusion: There is no significant difference noted among all the three categories in term of placental maturation and fetal weight measures.