Diffuse axonal injury: Epidemiology, associated risk factors and outcome: An institutional study from teritairy care centre in central India

Abstract

Aim: The aim of this study was to describe the outcome of patients with primary diagnosis of DAI and to identify clinical and sociodemographic factors associated with mortality and functional capacity 6 months after the injury. Materials and Methods: A total of 100 adult patients admitted in the department of neurosurgery between September 2019 and March 2021 with mild, moderate and severe traumatic brain injury (GCS ≤ 12) diagnosed to have DAI on CT and MRI, were included in this study. Patients were tracked for up to 6 months following discharge and their outcomes were graded as satisfactory or unsatisfactory using the Glasgow Outcome Scale Extended (GOS-E). Results: Most of the patients with Grade 1 DAI had satisfactory outcome at end of 6 months and most of Grade 3 Dai patients expired within 6 months post injury. Conclusion: The results of our study show that the outcome of DAI patients is determined by the severity of traumatic brain injury and the grade of DAI and is unaffected by patients age, gender, or TBI modality.