Comparison of procalcitonin and c-reactive protein as markers of neonatal sepsis

Abstract

Objective: To compare the clinical informative value of procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations in the detection of infection and sepsis and in the assessment of severity of sepsis.Study Design: This prospective study was conducted in Neonatology unit of department of pediatrics SKIMS, Srinagar. Study was conducted on 100 patient including preterm and term both.Results: In our study Sensitivity of CRP in detecting sepsis was found to be 77.78%, specificity 78.08%. In the present study Sensitivity of Procalcitonin in detecting sepsis was found to be 96.30%, specificity 69.86%.Conclusion: PCT is a better marker of sepsis than CRP.