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Abstract

Toxicology is a discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence toxicity includes the dosage, route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. Most chemicals display a classic dose response curve at a low dose (below a threshold), no effect is observed. Some show a phenomenon known as sufficient challengea small exposure produces animals that "grow more rapidly, have better general appearance and coat quality, have fewer tumors, and live longer than the control animals". Aquatic Pollution produced by the large amounts of waste material modifies the water in a negative manner. Such type of ecological changes occurs when harmful pollutants like heavy metals, pesticides, phenols and radioactive waste are directly or indirectly discharged into the aquatic ecosystems via industrial and urban effluents. In the present study Methanol was selected as Toxicant on fingerlings of freshwater fish Cirrhinus mrigala to understand the changes in lipid profile after acute exposure. It was observed that lipid profile decreased as the dose component was increased.