Prospective study of etiology, intervention, morbidity and mortality associated with sirs and mods following intra-abdominal infection and trauma

Abstract

Multiple organ failure is a major cause of morbidity and mortality in the critically ill patient. The syndrome involves the progressive dysfunction of the physiological system in the presence of Major injuries and operations for intra abdominal sepsis. This study was aimed at studying the incidence of systemic inflammatory response syndrome (SIRS) and multiple-organ dysfunction syndrome (MODS) in intraabdominal infections due to various causes, traumatic and non traumatic, mortality and morbidity associated and various interventions done for the patients. This study followed 200 patients in over 3 years. The incidence of SIRS and MODS in intraabdominal infection was found to be 11% and it accounts for 36.8% for all trauma admission. Mortality rate associated with SIRS and MODS appears to be 22%. There was a stronger correlation between observed and predicted mortality rate in SIRS and MODS score, there by indicating their greater usefulness in predicting the outcome.