Effect of preoperative systemic corticosteroids on intraoperative bleeding during sinonasal polyposis surgery

Abstract

This prospective study was done to evaluate the effect of preoperative systemic corticosteroids on intraoperative bleeding during sinonasal polyposis surgery. Materials and Methods: A Total of 70 patients with age between 10-60 years were studied from the in-patient department. All the cases meeting the inclusion and exclusion criteria underwent Diagnostic Nasal endoscopy, CT scan and were divided into 2 groups of 35 each. Group A (35) received oral prednisolone 1mg/kg/day for 5 days prior to surgery and Group B (35) severed as control. The patients were operated under general anaesthesia, the bleeding volume and surgical field visibility was recorded. Postoperatively patients were followed up once weekly for 4 weeks. Results: Better surgical field conditions were the results of the powerful anti-inflammatory and antiedematous activity of the drug, which facilitated blood and secretion evacuation from the operated area providing a better surgical field visibility. Conclusion: In conclusion pre-operative administration of oral steroids reduces intra-operative bleeding and early post-operative complications.