Antibacterial activity of ethanol extract of <em>Calotropis giganatea</em> leaves against <em>Staphylococcus aureus</em>, <em>Streptococcus pyogens</em>, <em>Salmonella typhi</em>, and <em>Pseudomonas aeruginosa</em>

Abstract

Calotropis gigantea is a common plant that most known for their medicinal properties, various categories of Phytochemical are present in this plant that have antibacterial, antifungal and anti allergic properties. In this study C. giganatea leaves is tested against selected bacteria to check the antibacterial activity. The ethanol extract of C. gigantea was tested against S. aureus, S. pyogens, S. typhi, P. aeruginosa for antibacterial testing. Antibacterial (Antimicrobial) testing is performed in vitro by Kirby-Bauer disc diffusion method in Muller Hinton agar. Extracts showing the antibacterial effects on selected tested organisms. Ethanol extracts show the maximum zone of inhibition against S. pyogens (20.5), lowest against P. aeruginosa (15.25). Minimum Inhibitory Concentration (MIC) was measured in mg/mL. Extracts showing the 13.5.4.5, 1.5, and 0.50 mg/Ml Minimum Inhibitory Concentration value for S. aureus, S. pyogens, S. typhi and P. aeruginosa, respectively.