Evaluation of pre-operative and post-operative endothelial cell counts in single-site versus twin-site phacoemulsification trabeculectomy: A Prospective, randomized study

Abstract

Introduction: Phacotrabeculectomy is a combined procedure in which both cataract extraction and glaucoma filtering surgery are performed in the same operative session. The one-site approach consists of both cataract extraction and trabeculectomy occurring through a single scleral incision. The two-site approach begins with cataract surgery, typically through a clear cornea incision, followed by a completely separate trabeculectomy performed superiorly upon completing the cataract procedure. This study looks at IOP changes, vision, loss of endothelial cells and BCVA between single-site and twin-site phacoemulsification -trabeculectomy surgeries, Methods: This prospective, randomized study was conducted between September 2014 to August 2015 with sample size of 80 subjects at National institute of Ophthalmology, Pune. Results: The endothelial cell loss was significantly more in single site surgery when compared to twin site surgery, in both at 1 month and 3 months follow-up time points (P-value