A study on serum ferritin and its correlation with metabolic syndrome

Abstract

Aim and Objective: To evaluate the relationship between serum ferritin and metabolic syndrome.Methods: The patients attending Rajah Muthiah Medical College & Hospital inpatient department are being screened for metabolic syndrome on the basis of NCEP: ATP III 2001 and harmonizing definition criteria. Based on the inclusion and exclusion criteria the patients are being enrolled into this study. Informed consent will be obtained from the patients before including them in the study.Materials and Methods:Design: Hospital based observational study.Place of Study: Department of General Medicine. Study Population: Cases attending the RMMCH inpatient department during the study period.Sample Size: 70.Study Period: November 2019 to April 2021.Results: In this study, we observed type 2 diabetes mellitus in 63 (90%) patients, systemic hypertension in 57 (81%) patients, elevated triglycerides in 28 (40%) patients, decreased HDL cholesterol in 13 (19%) patients and central adiposity was seen in all of the patients.In this study we were able to observe that serum ferritin which was elevated above average levels can be used as a marker for metabolic syndrome since ferritin is an acute phase reactant and metabolic syndrome is a pro inflammatory condition.Conclusion: There is a positive association between elevated serum ferritin (above average levels) and metabolic syndrome indicating it is a pro inflammatory condition.