Role of helicobacter pylori in oesophagitis

Abstract

Background: Reflux oesophagitis is defined as a condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications. Helicobacter pylori (H. pylori) is an important human pathogen involved in the pathogenesis of atrophic gastritis, gastro-duodenal ulcer, gastric cancer. The relationship between Reflux oesophagtis and H.pylori infection is still subject of debate.Aims: To evaluate treatment modality of H.pylori positive patients endoscopic followup and evaluate the incidence of reflux oesophagitis among the followup patients. To evaluate incidence of H.pylori infection in clinically diagnostic dyspeptic patients. To evaluate various modes of presentation.Study design: This is a prospective study done between October 2019 to September 2021 which includes 50 patients diagnosed with dyspeptic symptoms in RMMCH ChidambaramResults: Male population between 30 to 50 were the most affected among all. Lower socioeconomic group appear to be most affected. Majority of the patients had abdominal pain as the most common symptom. Majority of the patients who were treated with triple therapy had incidence of endoscopically proven lower end oesophagitisConclusion: As a result of appropriate treatment given to the hpylori positive patients, majority of the patients had successful eradication of Hpylori and subsequent incidence of endoscopically proven lower end oesophagitis. Thus helicobacter pylori could play a protective role in reflux oesophagitis.