Dexmedetomidine versus midazolam and fentanyl for monitored anaesthesia care in tympanoplasty under local anesthesia: Ramsay sedation score

Abstract

The most common discomforts that were faced by the patients of SMES under local anesthesia were noise during surgery and anxiety, followed by dizziness, backache, claustrophobia and ear ache. To reduce these discomforts, careful patient selection, adequate preparation for anesthesia, and appropriate sedation are necessary. All patients were randomly divided into two groups. Two 50-ml syringes, labelled as loading and maintenance were given for each patient. Group D patients had dexmedetomidine 1 μg/kg and Group MF had midazolam 0.05 mg/kg plus fentanyl 1.5 μg/kg in their respective loading syringes diluted up to 30 ml of normal saline. Group D 1μg/ml of dexmedetomidine and Group MF had normal saline in their respective maintenance syringes. Rescue infiltration was required in 8 patients in group D and 20 patients in group MF. Rescue sedation, infiltration & analgesia, were statistically significant between group D and group MF.