A study on the effect of vitamin d supplementation on primary dysmenorrhea: A prospective case control study

Abstract

Dysmenorrhea is a common problem among women of reproductive age group. The aim of this study is to investigate the effect of vitamin D supplementation in treatment of primary dysmenorrhea. A study was conducted on 60 women with primary dysmenorrhea and vit D deficiency referred to our OPD. Eligible women were randomly selected into treatment and control groups (30 in each group). Individuals in the treatment group received 50 000 IU oral vit D and the control group received placebo weekly for eight weeks. After two months of treatment, there was a significant difference in serum vit D concentration between the two groups (p< 0.001). Pain severity decreased in treatment group after eight weeks of treatment. There was a significant difference in pain intensity between the two groups after eight weeks of treatment. A weekly dose of (50 000 IU) oral vit D supplementation for eight weeks in patients with primary dysmenorrhea could improve pain intensity.