IV Ferric carboxymaltose versus iron sucrose in the treatment of iron deficiency anaemia of pregnant women

Abstract

Background: Anemia is defined as the reduction in absolute number of circulating red blood cells (RBC)s, indirectly measured by a reduction in hemoglobin (Hb) concentration, hematocrit (Hct) or RBC count. The present study was conducted to compare IV ferric carboxymaltose versus iron sucrose in the treatment of iron deficiency anaemia of pregnant women.Materials and Methods: 140 pregnant women were divided equally into 2 groups of 70 each. Group I received ferric carboxymaltose and Group II received iron sucrose. Haemoglobin, peripheral smear and serum ferritin was estimated to diagnose iron deficiency anaemia. Outcome was assessed by measuring haemoglobin 3 weeksResults: In group I, ferric carboxymaltose and in group II iron sucrose was given. Each group had 70 patients. The mean gestational age (weeks) was 32.4 and 31.7, packed cell volume was 27.1 and 27.5, mean corpuscular volume (fl) was 75.4 and 75.3, mean corpuscular haemoglobin (pg) was 29.6 and 29.5, mean corpuscular haemoglobin concentration (g/dL) was 29.9 and 30.2, serum ferritin (ng/L) was 11.7 and 11.3 and mean iron requirement (gms) was 845.3 and 890.4 in group I and II respectively.Conclusion: Both ferric carboxymaltose and iron sucrose found to be equally effective in women with iron deficiency anaemia