Evaluation of fetal hemodynamic changes and vascular adaptation to moderate and severe anemia in pregnancy

Abstract

Maternal anemia is associated with poor intrauterine growth, pre maturity and increased risk of preterm births and low birth weight rates, this leads to increase perinatal mortality and morbidity causing poor growth in infants, childhood and adolescence, and ultimately leads to adult low weight and height which in turn is a determinant for birth weight and intrauterine growth. Patients fulfilling inclusion criteria were included in the study after obtaining informed consent. Then they were categorized into moderate and severe anemia depending on their hemoglobin level. All hemoglobin level was estimated by Sahli’s method. Moderate anemia was defined as hemoglobin in between 7-10gm% and severe anemia if hemoglobin <7gm%. The MCA PSV was within 50-95th centile for gestational age in 92.9% for group 2,and 42.9% for group 1.while 57.1% group 1 and only 7.1% of group 2 cases were having MCA PSV values in between 5-50th centile for each gestational age. Mean CPR in group 1 was 2.05+/-0.45 and in group 2 was 2.02+/-0.39, the difference of which was not statistically significant.