Meta-analysis of urological complication between early vs late ureteric stent removal in kidney transplant recipient

Abstract

Introduction: The optimal timing of ureteric stent removal in kidney transplant recipients is still being debated. Therefore, meta-analysis is aimed to determine urological complicationsbetween early vs late ureteric stent removal in Kidney transplant recipients. Methods: The analysis compared major urological complications with urinary tract infections between early vs late ureteric stent removal in kidney transplant recipients. It was conducted using PRISMA guidelines and the Cochrane Handbook for Systematic Review of interventions. Data were collected after literature research, and analyzed using Review Manager 5.3. Results: 17 studies were conducted with various duration cut off points for stent removal. The incidence of urinary tract infections showed a significant decreased in the group with early ureteric stent removal. However, no difference of major urological complications was observed. Evidence showed the timing of stent removal should be determined early to reduce major urological complications and the incidence of urinary tract infections. Conclusion: There was no difference in the prevention of major urological complications between early and late stent removal. The incidence of urinary tract infections increased significantly in the group with late ureteric stent removal, hence, the 2 weeks cut off point in early state was the best timing for ureteric stent removal.