Phytochemical analysis and anthelmintic activity of stem of Cassia auriculata linn

Abstract

The present investigation aimed to screen the phytochemicals in the ethanolic and chloroform stem extracts of Cassia auriculata and evaluate their anthelmintic activity by using adult Indian earthworm Pheretima posthuma. Phytochemical screening of the extracts revealed the presence of Carbohydrates, Flavonoids, Phenols, Amino acids, Glycosides, Saponins, Fixed oils, Alkaloids, Phytosterols and Tannins. Chloroform and ethanolic extract of Cassia auriculata were investigated for anthelmintic activity using Albendazole (10 mg/ml) as standard reference and normal saline as control. The time to achieve paralysis and death of worm were determined. Chloroform extract shows more anthelmintic activity than ethanolic extract when compared with standard Albendazole.