Isolation and identification of Anthraquinones from the roots of Morinda Morindoides (Rubiaceae)

Abstract

Morinda Morindoides is a widely used plant in the traditional Ivorian pharmacopoeia, for the treatment of many microbial infections such as those due to amoeba, fungi, and is also used to treat diarrhea and rheumatic pain. The chemical composition of this species is very varied and includes numerous anthraquinones. In this article, we describe the isolation of a new Anthraquinone, 4-hydroxy-1-methoxy-2-methylanthraquinone (1) M Morindoides in conjunction with the known anthraquinones (2), 2-methylanthraquinone (3), Soranjidiol (4), Damnacanthol (5), Damnacanthal (6), Rubiadin-1-methyl-ether (7). The structures were elucidated through spectroscopic studies including 2D-NMR experiments (HSQC, HMBC, COSY, and NOESY).