Genetic polymorphisms in periodontal disease

Abstract

Periodontitis is a multifactorial disease occurs due to complex interaction between pathogenic bacteria and host response. Genes and environment plays a very important role and therefore, genetic factors are considered to be predisposing factor for the periodontal disease. The genetic polymorphisms influence the immune function and bone metabolism which are related to cause periodontitis. Only by carefully studying the genetics of a disease in populations we can hope to begin to unearth the complex interaction between genes and environment that underlie individual differences in disease susceptibility. So, to resolve, genetic susceptibility associated with periodontitis should be identified which might help to improve the diagnostic and treatment strategies.